Founder of a Groundbreaking Malign Melanoma Treatment Becomes Doctor Honoris Causa at Ch












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            * Founder of a Groundbreaking Malign Melanoma Treatment Becomes Doctor Honoris Causa at Ch
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            2. 6. 2011, By: P.K., Section: i-Forum informs, Translation: Jaroslav Švelch

            On June 2, Professor Patrick Anthony Riley, a world-renowned expert in pigment cell resear
            cancerous skin diseases, received the title of Doctor Honoris Causa in the historical buil
            Karolinum. The honorary title of the doctor of medicine was handed to him by his long-term

            and collaborator Professor Jan Borovanský.                                                
            Professor Riley’s experiments had led up to the clinical testing of 4- hydroxyanisole that
            becoming more widespread every year. “Pigment cells can transform amino acids into quinone
            an assumption that if we offer suitable substrates to the tyrosinase enzyme that can creat
                                                                                                      
            “Professor Riley’s main achievement is the introduction of the new type of treatment. That
            milimeter and is not removed in time, the prognosis is very unfavourable,” noted Professor
                                                                                                      
                                                                                                      
            Professor Riley has repeatedly taken part in the Czech scientific conferences in biochemis

            dermatology and is a member of the international editorial board of the Folia Biologica jo
            by the Charles University 1st Faculty of Medicine. Commenting on his recent collaboration 
            collegues, he said: “The first international monograph on melanosomes is coming out this J

            Wiley/Blackwell. Professor Borovanský and I have put together a team of authors and I beli
            going to be a success at this September’s congress in Bordeaux.”                          
            Professor Riley has collaborated with today’s Institute of Biochemistry and Experimental O
            and provided with them with chemicals that were unavailable in the country. It was mainly 
            centers in the field of melanins, melanosomes and malign melanomas.                       
                                                                                                      
            Prof. P.A. Riley [ URL "http://iforum.cuni.cz/IFORUM-11089.html"] , professor emeritus of 
            graduating in 1960. He joined the Department of Dermatological Histopathology at UCHMS as 
            scientific career), he demonstrated the distinct lineage of Langerhans cells and melanocyt
                                                                                                      
            From 1966 he worked in the Department of Pathological Chemistry, UCHMS, (which over the ye
            Pathology in 1984.                                                                        
            The scientific community recognises prof. Riley as a world expert and father of metabolica
                                                                                                      
            to unfavourable pharmacokinetics, the search for further cytotoxic tyrosine analogues has 
            significant publications dealing with quinones. This joint work generated novel data which
            Prof Riley is co-founder (and former Secretary) of the European Society for Pigment Cell R
                                                                                                      
            Address to the Assembled Faculties of Charles University, Prague [ URL "http://iforum.cuni

            IFORUM-11115.html"]